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Ceftiofur 5% Injectable Suspension



Contains per ml:
Ceftiofur (as hydrochloride) ……………  50 mg.
Solvents ad …………… 1 ml.

Ceftiofur is a semisynthetic, third generation, broad-spectrum cephalosporin antibiotic, which is administered to cattle and swine for control of bacterial infections of the respiratory tract, with additional action against foot rot and acute metritis in cattle. It has a wide spectrum of activity against both Gram-positive and Gram-negative bacteria. It exerts its antibacterial action by inhibition of cell wall synthesis. Ceftiofur is mainly excreted in urine and faeces.

Ceftiofur 5% oily suspension is indicated for treatment of the following bacterial diseases:
Cattle: For the treatment of bacterial respiratory disease associated with Pasteurella haemolytica (Mannheimia spp.), Pasteurella multocida and Haemophilus somnus. For the treatment of acute interdigital necrobacillosis (panaritium, foot rot), associated with Fusobacterium necrophorum and Bacteroides melaninogenicus (Porphyromonas asaccharolytica). For treatment of the bacterial component of acute post-partum (puerperal) metritis within 10 days after calving associated with Escherichia coli, Arcanobacterium pyogenes and Fusobacterium necrophorum, sensitive to ceftiofur.
Swine: Ceftiofur 5% oily suspension is indicated for treatment of bacterial respiratory disease associated with Pasteurella multocida, Actinobacillus pleuropneumoniae and Streptococcus suis.

Hypersensitivity to cephalosporins and otherβ-lactam antibiotics.
Administration to animals with a seriously impaired renal function.
Concurrent administration of tetracyclines, chloramphenicol, macrolides and lincosamides.

Side effects:
Mild hypersensitivity reactions may occur accasionally at the injection site, which subside without further treatment.

Bacterial respiratory infections: 1 ml per 50kg body weight for 3-5 days, subcutaneously.
Acute interdigital necrobacillosis: 1 ml per 50 kg body weight for 3 days, subcutaneously.
Acute metritis (0-10 days post partum): 1 ml per 50 body weight for 5 days, subcutaneously.
Swine: bacterial respiratory infections: 1 ml per 16 kg body weight for 3 days, intramuscularly.

Shake well before use and do not administer more than 15 ml in cattle per injection site and not more than 10 ml in swine. Successive injections should be administered at different sites.

Withdrawal times:
-For meat:
  Cattle    : 3 days.
  Swine    : 4 days.
-For milk    : 0 days.

Vial of 100 and 50 ml.

Keep out of reach of children.

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