Colistin Sulphate 1200000 IU & Amoxycillin Trihydrate 20% WSP

Composition:

Contains per gram powder:

Colistin Sulphate ……..………………………………………………………….. 1 200 000 IU.

Amoxycillin trihydrate …..…………………………………………………………..…. 200 mg.

Carrier ad ..……………..…………………………………………………………………… 1 g.

Description:

The combination of amoxicillin and colistin acts additive. Amoxicillin is a semisynthetic broad-spectrum penicillin with a bactericidal action against both Gram-positive and Gram-negative bacteria. The range of effect includes Campylobacter, Clostridium, Corynebacterium, E. coli, Erysipelothrix, Haemophilus, Pasteurella, Salmonella, penicillinase-negative Staphylococcus and Streptococcus, spp. The bactericidal action is due to inhibition of cell wall synthesis. Amoxicillin is mainly excreted in urine. A major part can also be excreted in bile. Colistin is an antibiotic from the group of polymyxins with a bactericidal action against Gram-negative bacteria like E. coli, Haemophilus and Salmonella. Since colistin is absorbed for a very small part after oral administration only gastrointestinal indications are relevant.

Indications:

Gastrointestinal, respiratory and urinary tract infections caused by amoxicillin and colistin sensitive micro-organisms, like Campylobacter, Clostridium, Corynebacterium, E. coli, Erysipelothrix, Haemophilus, Pasteurella, Salmonella, penicillinase negative Staphylococcus and Streptococcus spp., in calves, goats, poultry, sheep and swine.

Contra-indications:

Hypersensitivity to amoxicillin and/or colistin.
Administration to animals with a seriously impaired renal function.
Concurrent administration of tetracyclines, chloramphenicol, macrolides and lincosamides.
Administration to animals with an active microbial digestion.

Side effects:

Hypersensitivity reactions, renal dysfunction, neurotoxicity and neuromuscular blockade.

Dosage:

For oral administration:

Calves, goats and sheep: Twice daily 5 g per 100 kg body weight for 3 - 5 days.

Poultry and swine      : 1 kg per 1000 - 2000 litres of drinking water for 3 - 5 days.

Note: for pre-ruminant calves, lambs and kids only.

Please note: Before adding to the drinking water make a presolution of 1 kg Colistin Sulphate 1200000 IU +Amoxycillin Trihydrate 20% WSP per 20 liters of water with a temperature of 40º C.

Withdrawal times

- For meat: 8 days.

Warning

Keep out of reach of children.

Packing

Sachet of 100 g and jar of 500 and 1000 g.